Patrick Gray

My career has focused on drug discovery for critical diseases. I helped develop a vaccine for Hepatitis B and characterized numerous genes important for immunology and cancer. My laboratory became interested in cannabinoids after discovering they enhance immune function. Specifically, we identified certain cannabinoids that increase expression of the Major Histocompatibility Complex on tumor cells. This should improve the ability of the immune system to recognize and eliminate tumors. We are currently developing a cannabinoid-derived compound for treating glioblastoma. PAS-403 kills patient-derived glioblastoma cells in culture and also is effective in a mouse model of glioblastoma.