Shares of CannTrust Holdings Inc. tumbled 10% in premarket trade Thursday, after the Canada-based cannabis company reported a much wider than expected fourth-quarter loss and revenue that fell well short of analyst estimates. The company swung to a net loss of C$25.5 million ($19.0 million), or 26 cents a share, from a profit of C$6.3 million, or 8 cents a share, in the same period a year ago. The FactSet per-share consensus was a loss of 4 cents. Revenue rose to C$16.2 million ($12.0 million) from C$7.0 million, but missed the FactSet consensus of C$20.3 million. The company said the growth in sales, which was primarily due to growth in the medical patient base and recreational sales in Canada, was partially offset by the absorption of excise taxes. Total dried cannabis equivalent sold from extracts rose to 1.64 million grams from 0.46 million grams, while the average revenue per gram of cannabis fell to C$4.29 from C$9.34. Cash cost per gram sold fell to C$2.94 from C$5.16. Gross margin before fair value changes to biological assets declined to 35% from 69% in the sequential third quarter. The stock has more than doubled (up 108.2%) year to date through Wednesday, while the ETFMG Alternative Harvest ETF has climbed 44.9% and the S&P 500 has gained 11.9%.