The UCLA Cannabis Research Initiative (UCLA-CRI) is one of the first academic programs in the world dedicated to the study of cannabis. The UCLA CRI is supported by the UCLA Jane and Terry Semel Institute for Neuroscience and Human Behavior. Despite unprecedented access to cannabis, over half a century of research restrictions and limited funding have contributed to a lack of scientific knowledge about cannabis, particularly in regards to the potential therapeutic use. While our priority is to study the therapeutic potential and health risks of cannabis on the body, brain, and mind, our mission is to advance scientific understanding of the impacts of cannabis and hemp on body, brain, mind, and society.